The Protein Phosphatase 2A Regulatory Subunits B and B Mediate Sustained TrkA Neurotrophin Receptor Autophosphorylation and Neuronal Differentiation
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چکیده
منابع مشابه
Regulation of nerve growth factor signaling by protein phosphatase 2A
The goal of this dissertation research is to determine novel regulatory mechanisms of neurotrophin signaling mediated by protein phosphatase 2A (PP2A). PP2A is a ubiquitous Ser/Thr phosphatase that removes phosphates from proteins to switch their activity on or off. The substrate specificity and subcellular localization of PP2A is determined by almost 20 regulatory subunits that associate with ...
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